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Traveler's Shoes, Pythagorem's Piece, Sovereignty, Heartward Amulet, Pridwen, situational (e.g. Relic Dagger or Emperor's Armour). Sell boots lategame for Lono's Mask or Bumba's Mask or Staff of Myrddin or other.
Alternatively, go: Shoes of Focus, Gauntlet of Thebes, Jade Emperor's Crown, Void Stone/ Genji's Guard, Pridwen, situational. Sell boots lategame for Lono's Mask or Staff of Myrddin or Bumba's Mask or other.
I think best idea would be to ask EmilZy on his twitch stream or youtube comments what an Isis support build could be.
Also ideally you only need 20 to 30% CDR in a Isis build since her passive gives 10% CDR, and Potion of Magical Might also gives 10% CDR as well.