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I am level 30 on Smite, and I have a mastery level 6, almost 7 Isis, and these are the builds that I have found most effective for Isis. Also, this is my first (sort of) guide.
Eset can be played through incredible harassment, and amazing team fight presence, if used correctly.
Pros:
-Nice harassment
-Very good waveclear
-Utility stun
-Very good team fight presence
-Decent escape
-Good CC
-Good scaling
Cons:
-Can be squishy
-Weak early game
-Weak waveclear early game
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