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When using neith, your abilities drain your mana really fast so you dont want to be spamming abilities at the start. Only use abilities when you really need them. (e.g getting ganked and you need to stun with your 1 or getting charged and need to backflip).
All of this is true unless you get mana buff at the start which helps neith's laning greatly allowing her to use the 3-1-2 combo more and scare the enemy.
Once you hit Mid game, mana isnt to much of a problem for neith though it doesnt hurt to get some mana pots every now and again.
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