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General early game strategy:
Start with 1 health potion. Go to damage with mid laner and support at the start of the game. Clear the buff, give to the mid laner and then go clear purple with your support, and take the buff. Go to lane, if there before the enemies, kill the wave and aggressively push up. If you get to lane after your opponents, retreat to your tower while auto attacking minions.
Early laning phase:
Clear waves with your 2 while staying safe. If you have the creep advantage, throw auto attacks at the enemies. If you have creep disadvantage, stay back and clear creeps while not getting hit by the enemy adc or cced by the enemy support. Try and stay in lane to clear creeps until you can finish transcendence and buy 1 of each potion which will cost 2050. If you have to back before you can finish transcendence, get transcendence rank 2 and beads, as well as 1 of each potion or whatever you can buy.
Mid laning phase:
Continue safely farming creeps unless you know you can be aggressive. Once you have boots and asi, you can rotate around the map to gank or you can be more aggressive in lane since you have lifesteal to sustain. If you kill the enemy adc and mid laner, go for the Gold Fury with the support of your team. Buy beads and rank 2 sprint when you think it is appropriate.
Late game: Stay safe in the team fights until you see lots of enemy abilities down, and then attack the enemies while staying safe. Kill towers when enemies are dead. Listen to teammates calls on what to do.
Ability usuage:
Clearing wave, use your 2 and auto attacks to kill creeps. If you are initiating, use your ultimate to slow/stun, then use 2 and 1 to follow up on the target.
Gold fury fights, use your ult on the enemies as they are coming in or you are attacking them
Late game fights, start with your ult when you see an opening, if you stun someone, use your one and kill them. Beads any cc that is dangerous and sprint when you need to chase someone. Throw lots of auto attack and kill people.
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However, I disagree with how you use Medusa's ultimate. The key to using her ultimate right is counter initiation. You have to make the enemy team think that they are going to win the teamfight, then you ult them. If you start a fight with it, they will all just turn around and leave.
Alternatively, if you need to initiate with Medusa, you need to keep your ultimate in your back pocket. It will make the enemy afraid knowing that you have it, and they won't want to face you. If they do, you punish them.
The only time I would use it when they are turned around is if they are running away and you KNOW you can secure the kill.
(Your Gold Fury usage I'm ok with though)