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Ive been using Artemis for a while now and she is amazing, I've been tweaking with her build for a while now and this one just wrecks. By the time you get Bloodforge you doing as much damage as most other builds, and you gain extra health from killing gods to keep going or get away.
Warrior Tabi- Artemis is not an early gamer this has power and extra movement speed to get away when you need to.
DeathBringer-I like adding a crit item early because you can start doing some extra damage and picking off a few strays.
The executioner- More power and attack speed.
Bloodforge- I've seen devourer's gauntlets on builds a lot but with this you get more power even with the stacks to devourer's gauntlet ( I did the math) plus the ability of the item is quite nice wherein you get extra health for killing gods for a certain amount of time. Helps you stay in the battle longer.
Malice- Another crit item and more power.
Titan's bane- More power and 33% Physical penetration.
Artemis does use a lot of mana for her abilities so putting in trascendence might be nice but I go for mana camps and don't mind having to head back for healing. But everybody plays differently.
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