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Kali is a late game god. Play it safe early and mid game. Wait until you get your items online to really start doing risky moves. These builds have really worked for me and helped my Kali game. Always go for your kill target, the extra gold, pen and exp is critical to you getting ahead as Kali. This is my first submitted build here so if you guys have any questions or have anything to add here feel free guys.
Avoid leaping into an enemy and start attacking, always try to run up and start attacking. Save your leap for when they try to escape or if you need to escape. With fatalis you should be able to stick to them very easily.
Run in, use you 2, AA's until they try to bail. Then when they use the escape use your 1 to close the gap. Pop your 3 to stun then AA till death. Use your 2 on cooldown. I tend to use my 4 defensively. If a fight starts to go south pop your 4 and continue to kill or use your 1 and leap away. If they run under tower almost dead pop your 4 and run or leap in and shred them.